Who We Are


Nerve and Pain Institute is a comprehensive treatment center for neurological and painful conditions in the Portland metro area. Kwo Wei David Ho, MD, PhD, is the only pain physician with neurology training in the greater Portland area to provide you with both accurate neurological diagnosis and effective treatment. We believe in a personalized approach to your treatment, and we will provide the best possible care that is unique to you.

Our Providers

Kwo Wei David Ho, MD, Ph.D., is the lead physician at Nerve and Pain Institute. He is currently the only neurologist with interventional pain fellowship training in the Portland metro area. He completed his neurology residency and pain medicine fellowship training from Stanford University and moved to Portland to serve the local community. He is a leader in the field with over 30 peer-reviewed publications in pain medicine, neurology and neuroscience. He has undergone rigorous medical and scientific training through the Medical Scientist Training Program sponsored by the National Institute of Health, a highly selective program accounting for 1% of US-trained medical doctors. He is an active member of the American Academy of Neurology, American Academy of Pain Medicine, and North American Neuromodulation Society.
In addition to English, he speaks fluent Mandarin Chinese


Stanford University

  • Fellowship, Pain Medicine

University of Florida

  • Residency, Neurology

University of Iowa Carver College of Medicine, Medical Scientist Training Program (MSTP)

  • Doctor of Medicine
  • Doctor of Philosophy, Genetics

University of Virginia

  • Bachelor of Science, Chemistry with specialization in Biology
  • Bachelor of Arts, Physics


Ho KW, Wallace MR, Staud R, Filligim R. OPRM1OPRK1, and COMT genetic polymorphisms associated with opioid effects on experimental pain: a randomized, double-blind, placebo-controlled study. The Pharmacogenomics Journal (2019) doi:10.1038/s41397-019-0131-z. PMID 31806881

Ho KW. Introduction to the pediatric neuromuscular disorder: Adult perspective. In: Millichap JJ, Strowd RE, Pearl P, Mink JW, editors. Child Neurology: A Case-Based Approach: Cases from the Neurology R&F Section. Minneapolis: American Academy of Neurology; 2019: 34

Millichap JJ, Strowd R, Aamodt W, Adil MM, Delgado-Garcia G, Bushlin I, Claytor BR, Garrido-Sanabria ER, Gottlieb-Smith R, Ho KW. 2019 Annual Highlights of the Resident & Fellow Section. May 2019.

Lin HP, Ho KW, Jerath N. Late onset CMT2A in a family with an MFN2 variant: c.2222T>G (p.Leu741Trp). Journal of Neuromuscular Diseases. 2019;6(2):259-261. PMID: 31127728

Ho KW, Rempe T, Jerath N, Antony. Dorsal Root Ganglion Stimulation: A Potentially Effective Treatment for Painful Hereditary and Idiopathic Axonal Polyneuropathy (P2.6-067). Neurology. April 09, 2019; 92 (15 Supplement) (abstract)

Rempe T, Ho KW, Shahid M, Yang L, Chuquilin M. Neurofascin 140 and 155 antibodies in an atypical case of POEMS syndrome. Muscle & Nerve, 2019 Apr 24. PMID: 31018253

Ho KW, Rempe T, Jerath N, Antony A. Dorsal Root Ganglion Stimulation As a Potentially Effective Treatment for Painful Hereditary and Idiopathic Axonal Polyneuropathy: A Retrospective Case Series. Neuromodulation. 2019 Feb 14. PMID 30762923

Ho KW, Smith C, Chuquilin M, Bruzzone MJ. An unusual case of posterior column myelopathy. Journal of Clinical Neurocience. https://doi.org/10.1016/j.jocn.2018.12.012

Ho KW & Jerath N. T118M variant of PMP22 gene presenting with painful peripheral neuropathy– a case series and review of the literature. Case Reports in Genetics. 2018 Dec 25;2018: 2618071. PMID  30675404

Lin HP, Ho KW, Chuquilin M. Presence of both anti-contactin 1 and anti-neurofascin 140 antibodies in a case of chronic inflammatory demyelinating polyneuropathy. eNeurologicalSci. 2018 Nov 22;13:38-39. PMID: 30547099

Ho KW, Jerath NU.V144D Mutation of SPTLC1 Can Present with Both Painful and Painless Phenotypes in Hereditary Sensory and Autonomic Neuropathies Type I. Case Rep Genet. 2018 Oct 18;2018:1898151. PMID: 30420926

Mitchell SB, Iwabuchi S, Kawano H, Yuen TMT, Koh JY, Ho KW, Harata NC. Structure of the Golgi apparatus is not influenced by a GAG deletion mutation in the dystonia-associated gene Tor1a. PLoS One. 2018 Nov 7;13(11):e0206123. PMID: 30403723

Ho KW, Han S, Jancic D, Nielsen JV, Jancic D, Hing B, Fiedorowicz J, Bipolar Genome Study (BiGS) Consortium, Coryell W, Weissman M, Levinson DF, Potash J. Genome-wide association study of seasonal affective disorder. Translational Psychiatry, 2018, 8:190. PMID 30217971.

Ho KW & Jones R. Opinion and Special Articles: Pain Medicine: A Case for Neurologists. Neurology. 2018 Sept 4; 91(10): 483-486, PMID 30177530.

Ho KW & Jerath N. V144D mutation of SPTLC1 can present with both painful and painless phenotypes in hereditary sensory and autonomic neuropathies type I. Case Reports in Genetics, 2018;2018:3.

Wong J, Cauraugh J, Ho KW, Broderick M, Ramirez-Zamora A, Almeida L, Shukla A, Wilson C, Bie R, Weaver F, Kang N, Okun M. STN vs. GPi deep brain stimulation for tremor suppression in Parkinson’s disease: A systematic review and meta-analysis. Parkinsonism & Related Disorders, 2018 Aug 28. PMID 30177491.

Ho KW, Wallace M, Fillingim R. Association of OPRM1, OPRK1 and COMT gene polymorphism with opioid response is opioid and pain modality specific. Neurology, 2018; 90:15 (abstract)

Wong J, Gunduz A, Shute J, Eisinger R, Cernera S, Ho KW, Martinez-Ramirez D, Almeida L, Wilson C, Okun M, Hess C. Longitudinal Follow-up of Impedance Drift in Deep Brain Stimulation Cases. Tremor and Other Hyperkinetic Movements. 2018; 8:542, PMID 29607241

Ho KW, Przkora R, Kumar S. Sphenopalatine Ganglion: Block, Radiofrequency Ablation and Neurostimulation – A Systematic Review. The Journal of Headache and Pain. 2017, Dec; 18(1): 118. PMID 29285576

Ho KW, Wallace M, Sibille K, Bartley E, Cruz-Almeida Y, Gover T, King C, Goodin B, Addison A, Edberg J, Staud R, Bradley L, Fillingim R. Single Nucleotide Polymorphism in the COL11A2 Gene Associated with Heat Pain Sensitivity in Knee Osteoarthritis. Molecular Pain. 2017, Aug; 13. PMID: 28741447

Ho KW, Drew P, Chuquilin M. Merkel Cell Carcinoma with Distant Metastasis to the Clivus Causing Symptoms Mimicking Tolosa-Hunt Syndrome: A Case Report and Literature Review. Frontier Neurology. 2017, Aug; 8. PMID: 28868044

Ho KW, Wallace M, Fillingim R.B. Single-nucleotide polymorphism in COL11A2 associated with thermal hyperalgesia in knee osteoarthritis. Neurology. 2017, Apr; 88(16): P1.210 (abstract)

Ho KW, Wallace M, Fillingim R.B. A SNP in COL11A2 associated with thermal hyperalgesia in patients with knee osteoarthritis. Journal of Pain. 2017, Apr; 18(4): S74–S75. (abstract)

Foad E, Reddy C, Ho KW. Ultrasound Guided Peripheral Nerve Stimulation Implant for Management of Intractable pain after Inguinal Herniorrhaphy. Pain Physician. 2015, Jan; 18(1): 31-38. PMID: 25675068

Foad E, Ho KW. Successful management of refractory headache and facial pain due to cavernous sinus meningioma with sphenopalatine ganglion radiofrequency. Case Report in Neurological Medicine. 2014, Sep, Article ID 923516. PMID: 25343051

Foad E, Ho KW. Anesthesia dolorosa of trigeminal nerve, a rare complication of acoustic neuroma surgery. Case Report in Neurological Medicine. 2014, Sep, Article ID 496794. PMID: 25328729

Iwabuchi S, Koh JY, Wang K, Ho KW, Harata NC. Minimal Change in the Cytoplasmic Calcium Dynamics in Striatal GABAergic Neurons of a DYT1 Dystonia Knock-In Mouse Model. PloS one. 2013, Nov; 19(8): e80793. PMID: 24260480

Kakazu Y, Koh JY, Ho KW, Gonzalez‐Alegre P, Harata NC. Synaptic vesicle recycling is enhanced by torsinA that harbors the DYT1 dystonia mutation. Synapse. 2012, Feb; 66(5): 453-464. PMID: 22213465

Xu Q, Kim M, Ho KW, Lachowicz P, Fanucci GE, Cafiso DS. Membrane hydrocarbon thickness modulates the dynamics of a membrane transport protein. Biophysical Journal. 2008, Jun; 95(6): 2849-2858. PMID: 18586842

Lukasik SM, Ho KW, Cafiso DS. Molecular basis for substrate-dependent transmembrane signaling in an outer-membrane transporter. Journal of Molecular Biololgy. 2007, May; 370(5): 807-811. PMID: 17555764